Tenders/BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)

National Institutes of Health
Published: May 4, 2026
Updated: Jun 14, 2026
Source: grants_gov

About This Opportunity

Grant contract by National Institutes of Health (United States): BRAIN Initiative: Exploratory Research. healthcare. Submission deadline Feb 2027.

This is a grants contract in the health and medical services and Research sectors, with a focus on Medical Equipment. Located in United States, North America, this opportunity is open to firms and consortiums, with an estimated budget of USD 700,000. Proposals must be submitted before February 11, 2027.

Published through Grants.gov, a national government procurement portal. Public procurement tenders follow the country's national bidding regulations and may have specific eligibility and documentation requirements for grants in the health and medical services sector. Grant applications generally require a detailed project proposal, a clear results framework, and evidence of the applicant's capacity to deliver the proposed activities. Interested parties should review the full documentation on the original source before submitting their proposal.

Description

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent research project grant applications using invasive neural recording and stimulation technologies in the human brain. Projects should maximize opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate.
Recipients will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

Agency: National Institutes of Health

CFDA: 93.242, 93.173, 93.286, 93.866, 93.273, 93.279, 93.865, 93.853, 93.213, 93.867

Eligible Applicants: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Applicant Types: Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; City or township governments; State governments; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education

Cost Sharing: No

Contact: National Institutes of Health

Email: BRAINeROH@ninds.nih.gov

Data provenance

This notice is sourced from Grants.gov and was originally published on May 4, 2026. Last refreshed 16 days ago. BidsFactory mirrors official procurement notices and links back to the source for full legal text.

About National Institutes of Health

National Institutes of Health has issued 83 procurement notices on BidsFactory, including 81 currently open and 0 awarded contracts. Activity concentrates in Health & Medical, Research & Innovation, and Information & Communication Technology. All notices are published for United States. Notices are distributed via Grants.gov. Most recent publication: June 26, 2026.

Frequently asked questions about this tender

What type of contract is this?

This is a Grants contract in the Health & Medical sector. The classification helps bidders match the opportunity to their qualifications and registered scope of supply.

What is the estimated budget?

The estimated contract value is Up to $700,000. Bidders should ensure their proposals are consistent with this range and account for any local taxes and contract execution costs.

Where will the contract be performed?

The contract is for delivery in United States. Foreign bidders should review local registration, taxation, and any in-country presence requirements before submitting.

How can I submit a bid?

Visit Grants.gov to access the full notice, required documents, and submission instructions provided by the contracting authority.

When does this tender close?

The submission deadline is February 11, 2027. You have 226 days left to prepare and submit your proposal to the contracting authority.

Who is the contracting authority?

This notice was issued by National Institutes of Health in United States. The authority is responsible for evaluating bids, awarding the contract, and managing performance.

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Key Details

Submission Deadline
Feb 11, 2027
226 days remaining
Estimated Budget
Up to $700,000
Contract Type
Grants
Eligibility
Firms / Consortiums
Language
English

Source

grants_gov
grants_gov
Official Source

Contracting Authority

National Institutes of Health
🇺🇸United States

Contact

Contact Person
National Institutes of Health

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