Modernization of a 400 MHz NMR spectrometer system using the existing magnet

The subject of the procurement is the modernization of the existing NMR infrastructure of the Leibniz Institute of Plant Biochemistry (IPB) and the expansion of the existing software environment for managing NMR spectral data. Lot 1 includes the delivery, installation, and commissioning of a modern 400 MHz NMR spectrometer system using the existing magnet (Type 400/54/ASP, year of manufacture 2011). The scope of services particularly includes the replacement of the existing system console with a current, high-performance console, including all necessary components such as high-frequency units, amplifiers, gradient systems, and other system components. Furthermore, Lot 1 includes the delivery of suitable probes (including a nitrogen-cooled probe to increase sensitivity), an automated sample changer, the required control and evaluation software, and a control computer with peripherals. The services also include full integration into the existing infrastructure, installation, commissioning, as well as training and service. All offered components must be fully compatible with the existing NMR magnet. All adjustments, additions, and interfaces required for integration are part of the service. The system must be designed for applications in natural product chemistry, metabolomics, and synthetic analytics. It must be particularly suitable for one-dimensional and multi-dimensional NMR measurements and ensure high sensitivity for the analysis of low-concentration samples. This includes, among other things, measurements of various nuclei as well as gradient-based and multi-dimensional NMR experiments, including modern data processing. Lot 2 includes the delivery and implementation of a software solution for managing an NMR spectral library. The software is to be provided as an extension of the existing MNova software environment (Mestrelab Research) and integrated as an upgrade into the existing workflows. The goal is the organization, storage, processing, and evaluation of NMR spectral data within the scope of a planned reference substance library. The scope of services for Lot 2 specifically includes the provision of a server-based software solution, suitable client licenses, update and support services, as well as conducting user training. Bidders are offered the opportunity for an on-site inspection to assess the technical conditions. Participation is expressly recommended to consider the existing system environment.